Order Comprehensive DFNB1 and STRC Panel for Hearing Loss
The Comprehensive DFNB1 and STRC panel assesses for the presence of variants in the two most common causes of autosomal recessive nonsyndromic hearing loss, the GJB2 (DFNB1 locus) and the STRC genes. Both sequencing and the most common copy number variants in these genes are identified, including the contiguous gene deletion of STRC and CATSPER2, associated with Deafness and Male Infertility syndrome. Read more details about this test.
Requisition Form
All samples must be accompanied with a completed requisition form. Please make sure any identifiers used on the specimens are provided on the paperwork. Consent page should be signed by a health care provider. Any incomplete or missing paperwork may delay the start of testing
Test Detail
GJB2, GJB6, STRC, CATSPER2
- Next Generation Amplicon Based Sequencing of GJB2 and STRC
- Sanger confirmation of variants identified and fill in for low coverage
- STRC, CATSPER2, and GJB6 (DFNB1) deletion analysis via droplet digital PCR
Ordering
lmOto-pnlP_L
4-6 weeks
7ml of whole blood (3–5ml for an infant) in a lavender top tube (K2EDTA or K3EDTA)
OR
10 ug of DNA at a minimum concentration of 25 ng/ul (please provide DNA concentration)
Billing Information
The Laboratory for Molecular Medicine offers several billing options for our clients and their patients; however, we do not bill insurance companies and are unable to begin testing without accurate billing information.
81252, 81254, 81479
$1450
