Order Auditory Neuropathy/Dys-synchrony Panel (OTOF and DFNB59)
Auditory neuropathy spectrum disorder (ANSD) includes hearing loss, previously described as either auditory neuropathy or auditory dyssynchrony. Variants in the OTOF gene, encoding otoferlin, underlie the DFNB9 form of hearing loss, best characterized by nonsyndromic prelingual moderate-profound sensorineural hearing loss often presenting as ANSD. Read more about this test.
All samples must be accompanied with a completed requisition form. Please make sure any identifiers used on the specimen are provided on the paperwork. Consent page should be signed by a health care provider. Any incomplete or missing paperwork may delay the start of testing.
- Next Generation Sequencing (copy number analysis included when data meets quality standards)
- Sanger Confirmation
7ml of whole blood (3–5ml for an infant) in a lavender top tube (K2EDTA or K3EDTA)
10 ug of DNA at a minimum concentration of 25 ng/ul (please provide DNA concentration)
The Laboratory for Molecular Medicine offers several billing options for our clients and their patients; however, we do not bill insurance companies and are unable to begin testing without accurate billing information.
81405 (1), 81479 (1)
For questions, please contact us at 617-768-8500 or by email.