Robert C. Green MD, MPH
Robert C. Green, MD, MPH is the Associate Director for Research at Partners Personalized Medicine. He is also a medical geneticist, physician and public health researcher who directs the Genomes2People (G2P) Research Program (genomes2people.org) in translational genomics and health outcomes in the Division of Genetics at Brigham and Women’s Hospital and Harvard Medical School.
Dr. Green is principal investigator of the MedSeq Project, the first NIH-funded randomized trial to explore the use of whole genome sequencing in the clinical practice of medicine, and co-directs the BabySeq Project, the first NIH-funded trial of sequencing in newborns. The MedSeq and BabySeq Projects utilize genome sequencing both in patients who are affected with hereditary disease and in those who are healthy, in order to study downstream impact on health, behavior and healthcare costs. Dr. Green is also principal investigator of the NIH-funded REVEAL Study, in which a cross-disciplinary team has conducted five separate multi-center randomized clinical trials since 2000, collectively enrolling 1,100 individuals in order to explore emerging themes in translational genomics. The goal of the current REVEAL trial, REVEAL-SCAN, is to examine the impact of learning amyloid imaging results in cognitively normal individuals. Dr. Green also co-directed the NIH-funded PGen Study, one of the first prospective studies of direct-to-consumer genetic testing services.
Dr. Green is a Board Member of the Council for Responsible Genetics and a member of the Informed Cohort Oversight Boards for both the Children’s Hospital Boston Gene Partnership Program and the Coriell Personalized Medicine Collaborative. He was lead author of the published recommendations from the American College of Medical Genetics and Genomics for management of incidental findings in clinical sequencing. He recently co-chaired the Steering Committee of both the Clinical Sequencing Exploratory Research program (18 NIH grants, over 300 investigators), and currently co-chairs the Steering Committee of the Newborn Sequencing in Genomic Medicine program (4 NIH grants, over 100 investigators) and is a co-investigator in the recently awarded Partners project as member of the Electronic Medical Records and Genomics Network. He is also a member of the Executive Committee for the Partners BioBank.